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THIOCARBAMATES

Examples of Commercial Products and Generic Names

 
Caplan (Thalamide group)(Captan)
Dithianon(Delan)
Maneb(Dithene, Polytram)
Mancozeb(Manzate, Nemispor, Pencozeb, Sancozeb)
Thiobencarb(Saturn)
 

Pharmacological Action or Site of Toxicity

Neurotoxic
Skin irritant
Inhibition of aldehyde dehydogenase

Routes of Absorption

Ingestion
Dermal
Inhalation

WHO Hazard Classification

Class II-III

Symptoms

WITHOUT ALCOHOL INGESTION. Itching, redness, dermatitis, hoarseness, coughing, nausea, vomiting, ataxia, muscle weakness, .paralysis.

WITH ALCOHOL INGESTION.(Due to aldehyde dehydrogenase inhibition). Flushing sweating shortness of breath, chest pain, hypertension.

Treatment

  1. Decontaminate, Wash skin and hair for ingestion, lavage using activated charcoal.
  2. Supportive therapy
  3. If complicated with alcohol, oxygen as needed and Vitamin C.
  4. No alcohol for three weeks in any case.

Lab Tests

No simple test. Only complex laboratory procedures.

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Pakistan Agricultural Pesticides Association

909-910, Park Avenue, P.E.C.H.S.,
Shahrah-e-Faisal,
Karachi-75400

Tel:454 1562 Fax:454 6131