Main

Search by Brand

CARBAMATES

Aldicarb(Temik)
Carbosulfan(Advantage)
Carbofuron(Brifur, Curaterr, Furadan, Sunfuran)
Cartap(Padan)
Carbaryl(Sevin)
Dithiocarbamate(Antroacol)
Furathiocarb(Deltanet)
Methomyl(Lannate, Nudrin)
Pirimicarb(Pirimor)
Thiofanox (Decamox) 
Triazamate (Aztec)

Pharmacological Action or Site of Toxicity

Anticholinesterase
(Reversible)

Routes of Absorption

Ingestion
Inhalation
Dermal

WHO Hazard Classification

Class 1-III

Symptoms

Blurred Vision, disturbances of accommodation, Retrobulbar pain, constriction of pupils, Salivation, Profuse sweating, Lassitude, Muscle in-coordination, Nausea, Vomiting, Diarrhea, Epigastric pain, Tightness in chest.

Treatment

SPEED IS IMPERATIVE

Persons giving first aid should avoid contact with contaminated clothing and  vomitus.

  1. Maintain adequate respiratory and cardiac functions. Keep airway open, aspirate, use oxygen, insert endotraceal tube. artificial respiration and tracheotomy in severe cases.
  2. FOR EXTREME SYMPTOMS OF  POISONING INJECT ATROPINE I.V. (1-3 mg) EVERY 5-10 MINUTES UNTIL SIGNS OF ATROPINIZATION OCCURS.
    Signs of atropinization includes dry flushed skin, pupillary size of at least 4 mm, & heart rate of 120/min. Do not give atropine to a cyanotic patient. Give artificial respiration first then administer atropine I.M. or S.C. Atropine prophylaxis is not recommended.
    In case of "Padan" I.V. Injection of 100-200 mg L-cystine or I.M injection of 20-60 mg of BAL are recommended by the manufacturer.
  3. For skin contact, wash with soap and water. Use  rubber gloves while washing contact areas.
  4. For ingestion, lavage with activated charcoal slurry (100 gm charcoal in 150 ml water).

  5. AVOID MORPHINE, THEOPHYLLINE, AMINOPHYLLINE, OR BARBITURATES

  6. 2-PAM or TOXOGONIN IS CONTRA-INDICATED therefore do not use it.

Lab Tests

Red cell cholinesterase test.
Levels 30-50% of normal indicate exposure, although symptoms may not appear until the level falls to 20% or less. Values may return to normal within 12 to 72 hrs. depending on severity of poisoning.

1-naphthol, normally found in traces, is excreted in urine in much higher concentration following Carbaryl (Sevin) ingestion.

Serum cholinesterase test to be done.

BACK

 

Pakistan Agricultural Pesticides Association

909-910, Park Avenue, P.E.C.H.S.,
Shahrah-e-Faisal,
Karachi-75400

Tel:454 1562 Fax:454 6131